What Maya's brief found
Real findings ranked by how many independent specialist agents converged on them. Each comes with a specific question to bring to her care team.
Strong
The Cunningham Panel — a test her pediatrician didn't mention
A specialized autoantibody panel developed at the University of Oklahoma to identify the specific antibodies driving PANDAS/PANS symptoms (anti-D1, anti-D2, anti-tubulin, anti-lysoganglioside, CaMKII activation). Endorsed by the PANS Research Consortium. Many general pediatricians don't order it because they don't know it exists.
"Can we run a Cunningham Panel to identify which specific autoantibodies are driving her symptoms?"
Promising
Targeted Immune Modulation Beyond IVIG
For plateau cases like Maya's, emerging research supports adjunctive immune modulators alongside IVIG. Metformin and Low-Dose Naltrexone (LDN) have published case reports in PANS for NK-cell rebalancing and neuroinflammation reduction. Both are off-label, well-tolerated, and inexpensive.
"Given her NK cell levels, would adjunctive Metformin or LDN be reasonable to consider alongside IVIG?"
Promising
Mitochondrial & Gut-Brain Support
Sodium butyrate, Urolithin A, CoQ10, and NAD+ precursors have emerging research for supporting mitochondrial function and gut-barrier integrity — both linked to fatigue cycles and persistent neuroinflammation.
"Could a mitochondrial assessment or microbiome testing offer new insight into her plateau and energy cycles?"
Act now
Hormonal & Nutritional Reassessment
Chronic inflammatory conditions deplete zinc, vitamin D, selenium, and can disrupt DHEA in adolescent girls — all correctable contributors to mood, energy, and concentration.
"Should we run a comprehensive hormonal and micronutrient panel to identify deficiencies slowing her recovery?"
Maya's full brief was 47 pages. Yours will be tailored to your specific question.
Why $99
At a top academic center — Mayo Clinic, MD Anderson, Cleveland Clinic — your case might be reviewed by 5-7 sub-specialists in a tumor board. That access takes weeks of referrals, often travel, and runs $2,000–$5,000 just for the consult.
Insight Swarm convenes 14 specialist agents for your case. Same shape of analysis. 48 hours instead of 6 weeks. $99 instead of $5,000+.
| Where | Cost | Time |
|---|
| Mayo / MD Anderson tumor board | $2,000–5,000 | 4–8 weeks |
| Patient advocacy services | $300–2,000 | days of intake |
| ChatGPT or Perplexity | free, won't search PubMed correctly | minutes |
| Insight Swarm | $99 | 48 hours |