AI-Powered Glioblastoma Research

GBM is the most aggressive primary brain tumor. AI agents research blood-brain barrier penetration strategies, immunotherapy, tumor-treating fields, and novel compounds.

Standard of Care

Surgical resection, temozolomide + radiation (Stupp protocol), tumor-treating fields (Optune), bevacizumab.

Prevalence

~13,000 new GBM diagnoses per year in the US.

Five-Year Survival

~6.8% overall. Median survival ~15 months with standard treatment.

Key Mutations

Key Pathways

Clinical Trial Focus

CAR-T for GBM, oncolytic virus (DNX-2401), convection-enhanced delivery, neoantigen vaccines.